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ÐÓ°ÉÔ­´´ Medical Center scientists have identified a C. diff protein system that senses and captures heme (part of hemoglobin) to build a protective shield that fends off threats from our immune system and antibiotics.

After evaluating the ability of more than 1,500 monoclonal antibodies to bind and neutralize the COVID-19 virus, SARS-CoV-2, in the laboratory, AstraZeneca signed an exclusive license to six candidate antibodies in ÐÓ°ÉÔ­´´’s portfolio.

Staph bacteria may change the factor they use to activate blood clotting — to evade the immune response — a new study suggests.

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

ÐÓ°ÉÔ­´´ researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis.

The investigational antiviral drug remdesivir can shorten the time to recovery in adults hospitalized with COVID-19, according to preliminary results of a clinical trial published last month in The New England Journal of Medicine.

People with cancer sickened by COVID-19 have a crude death rate of 13%, according to the largest series of data released thus far from a multinational perspective. The data on more than 900 patients also revealed cancer-specific factors associated with increased mortality.

Renã Robinson, associate professor of chemistry, has been immersed in science-related activities and classes since she was a child. Today, she is leading a diverse lab of researchers, using chemistry to uncover clues surrounding Alzheimer’s disease. Read More

Jonathan Irish joins an international collaboration by deploying artificial intelligence to optimize COVID-19 treatment and vaccine development. Read More

A new paper proposes an ethical way to test drug safety during pregnancy by using electronic health data to conduct "virtual" drug trials.

Lung disease experts at ÐÓ°ÉÔ­´´ Medical Center and their colleagues have determined a key factor as to why COVID-19 appears to infect and sicken adults and older people preferentially while seeming to spare younger children.

Nancy Carrasco has found that the environmental pollutant perchlorate, found in drinking water in 49 states, is more dangerous than we knew. Read More

Kate Clouse is working with researchers at the University of Cape Town to develop a phone app that will help new mothers with HIV in South Africa stay connected to the healthcare system during the perinatal period.

As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at ÐÓ°ÉÔ­´´ Medical Center.

Researchers are using imaging and diagnostic pathology to examine postmortem hearts donated by victims of COVID-19 to gain a better understanding of how the coronavirus that causes COVID-19 affects the heart.

As Nashville cautiously begins to emerge from its two-month-long COVID-19 Safer at Home response, so too are the labs and facilities at ÐÓ°ÉÔ­´´ Medical Center.

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

ÐÓ°ÉÔ­´´ researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device.

Researchers at ÐÓ°ÉÔ­´´ Medical Center are leading a nationwide study to determine the rate of novel coronavirus infection in U.S. children and their families.

Rates of neonatal abstinence syndrome have plateaued after 20 years of increasing frequency across the country, according to a new study published in Health Affairs.